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STAT3 | D. Stoiber-Sakaguchi
Tuesday, 16. July 2024

The protein STAT3 helps the immune system to recognise leukemic cells. This interaction, which is important for future immunotherapies, is now understood in detail thanks to a study at the Karl Landsteiner University of Health Sciences (KL Krems). The study showed that STAT3 influences the formation of surface structures on leukemic cells that make them vulnerable to the immune system. If these structures are missing, leukemic cells can escape the body's innate immune surveillance. The expression of STAT3 in and the surface structures on leukemic cells could be a potential biomarker for future immunotherapies.

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A study at the Karl Landsteiner Private University for Health Sciences (KL) investigated the theoretical significance of self-organisation for illness-related uncertainty in the course of chronic illness.

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“Social distancing” was and still is one of the most important strategies against the spreading of Covid-19. The motivation to maintain contact restrictions is therefore important for the containment of the pandemic. Differently formulated appeals affect willingness for compliance in people.

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Azacitidine is commonly used to treat a subset of blood cancers in patients unfit for chemotherapy. Doctors from all over Austria have recorded the occurrence of adverse events with this agent in a real-world setting. A team from the University Hospital of Krems and the Karl Landsteiner University participated in this study.

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Daily feelings of hunger can be linked to negative emotionality. This is what researchers at the Karl Landsteiner University of Health Sciences (KL) found in a study that was recently published in the renowned scientific journal PLOS ONE. The experience-sampling project with student participation on "hangry", the simultaneous occurrence of feelings of hunger and negative emotions, was conducted together with Anglia Ruskin University, UK. The special feature: an app developed at KL made this research possible in the "field", i.e. in the everyday life of the participants.

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Lower Austrian Medical Association urgently appeals to doctors and the public to donate blood. Operations have already had to be postponed due to a lack of blood reserves.

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D.O.T. research group developed analogue and digital measures to promote mental health in children and young people.
How can children in difficult life situations be supported in their personal development and in their social environment? This central question of mental health care was addressed by the international and interdisciplinary research group within the framework of the project "D.O.T. - The Open Door". At the online final conference at the Karl Landsteiner University of Health Sciences (KL) at the end of June 2022, the highlights of four years of research work were now presented.

Andreas Farnleitner
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The 4th European Calcium Channel Conference in Alpbach presented the latest research findings.

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The transition from primary school to secondary school is challenging for children. Stressful circumstances such as parental separation, bullying or learning difficulties hamper transition. Those affected want concrete support services.

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Study by Karl Landsteiner University for Health Sciences demonstrates partial superiority of artificial intelligence and physiological image data in brain tumor classification

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Large study with adolescents examined correlations between social media use and cognitive abilities

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The increasing number of bone fractures in old age is causing more orthopaedic prostheses implanted. The metal screws that are currently used to fix implants are prone to complications. Orthopaedic screws need to be tested for their holding capacity before using them in humans.

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