Prospective analysis of radiation-induced contrast enhancement (RICE)
... and health-related quality of life following proton therapy for CNS and skull base tumors
Recent publication
This prospective study investigated the incidence, characteristics and risk factors of radiation-induced contrast enhancement in the brain after proton radiotherapy. Contrast enhancement was detected in 15% of 421 patients between 2017 and 2021, with an average follow-up of 24 months. Risk factors were identified and the impact on quality of life was assessed using a questionnaire. The international collaboration included researchers from the Division of Biostatistics and Data Science at Karl Landsteiner University and the Division of Radiotherapy - Radiation Oncology at Krems University Hospital. The study was led by scientists at MedAustron, which is a teaching and research site of the Karl Landsteiner University. The work has been published in the International Journal of Radiation Oncology*Biology*Physics.
Lütgendorf-Caucig C, Pelak M, Hug E, Flechl B, Surböck B, Marosi C et al. Prospective analysis of radiation-induced contrast enhancement (RICE) and health-related quality of life following proton therapy for CNS and skull base tumors. International Journal of Radiation Oncology Biology Physics. 2024 Jan 18. Epub 2024 Jan 18. doi: 10.1016/j.ijrobp.2024.01.007
Prim. Clin. Assoc. Prof. PD Dr. Petra Georg MBA
Division of Radiotherapy - Radiation Oncology (University Hospital Krems)